Bulk and single-cell transcriptome analyses of islet tissue unravel gene signatures associated with pyroptosis and immune infiltration in type 2 diabetes

Bulk and single-cell transcriptome analyses of islet tissue unravel gene signatures associated with pyroptosis and immune infiltration in type 2 diabetes

IntroductionType 2 diabetes (T2D) is a common chronic heterogeneous metabolic disorder. However, the roles of pyroptosis and infiltrating immune cells in islet dysfunction of patients with T2D have yet to be explored. In this study, we aimed to explore potential crucial genes and pathways associated...

Full description

Bibliographic Details
Main Authors: Yaxian Song, Chen He, Yan Jiang, Mengshi Yang, Zhao Xu, Lingyan Yuan, Wenhua Zhang, Yushan Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Endocrinology
Subjects:
differentially expressed gene
type 2 diabetes
pyroptosis
immune infiltration
single-cell RNA
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1132194/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1132194/full

Similar Items