Natural Exposure- and Vaccination-Induced Profiles of Ex Vivo Whole Blood Cytokine Responses to Coxiella burnetii

Natural Exposure- and Vaccination-Induced Profiles of Ex Vivo Whole Blood Cytokine Responses to Coxiella burnetii

Q fever is a zoonotic disease caused by the highly infectious Gram-negative coccobacillus, Coxiella burnetii (C. burnetii). The Q fever vaccine Q-VAX® is characterised by high reactogenicity, requiring individuals to be pre-screened for prior exposure before vaccination. To date it remains unclear w...

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Bibliographic Details
Main Authors: Susan Raju Paul, Anja Scholzen, Ghazel Mukhtar, Stephanie Wilkinson, Peter Hobson, Richard K. Dzeng, Jennifer Evans, Jennifer Robson, Rowland Cobbold, Stephen Graves, Mark C. Poznansky, Anja Garritsen, Ann E. Sluder
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
Coxiella burnetii
Q fever
vaccination
infection
cytokines signature
human
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.886698/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.886698/full

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