Differential gene co-expression network analyses reveal novel molecules associated with transcriptional dysregulation of key biological processes in osteoarthritis knee cartilage

Differential gene co-expression network analyses reveal novel molecules associated with transcriptional dysregulation of key biological processes in osteoarthritis knee cartilage

Objectives: To compare co-expression networks of normal and osteoarthritis knee cartilage to uncover molecules associated with the transcriptional misregulation compromising biological processes (BPs) critical for cartilage homeostasis. Design: Normal and osteoarthritis human knee cartilage RNA-seq...

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Bibliographic Details
Main Authors: I. Buzzatto-Leite, J. Afonso, B. Silva-Vignato, L.L. Coutinho, L.E. Alvares
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Osteoarthritis and Cartilage Open
Subjects:
Osteoarthritis
Knee cartilage
PCIT
RNA-Seq
Epigenetics
Transcription regulation
Online Access:http://www.sciencedirect.com/science/article/pii/S266591312200084X

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http://www.sciencedirect.com/science/article/pii/S266591312200084X

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