Regulatory architecture of housekeeping genes is driven by promoter assemblies

Regulatory architecture of housekeeping genes is driven by promoter assemblies

Summary: Genes that are key to cell identity are generally regulated by cell-type-specific enhancer elements bound by transcription factors, some of which facilitate looping to distant gene promoters. In contrast, genes that encode housekeeping functions, whose regulation is essential for normal cel...

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Bibliographic Details
Main Authors: Marion Dejosez, Alessandra Dall’Agnese, Mahesh Ramamoorthy, Jesse Platt, Xing Yin, Megan Hogan, Ran Brosh, Abraham S. Weintraub, Denes Hnisz, Brian J. Abraham, Richard A. Young, Thomas P. Zwaka
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Cell Reports
Subjects:
CP: Molecular biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723005168

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http://www.sciencedirect.com/science/article/pii/S2211124723005168

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