The Role of Nitric Oxide in Cancer: Master Regulator or NOt?

The Role of Nitric Oxide in Cancer: Master Regulator or NOt?

Nitric oxide (NO) is a key player in both the development and suppression of tumourigenesis depending on the source and concentration of NO. In this review, we discuss the mechanisms by which NO induces DNA damage, influences the DNA damage repair response, and subsequently modulates cell cycle arre...

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Bibliographic Details
Main Authors: Faizan H. Khan, Eoin Dervan, Dibyangana D. Bhattacharyya, Jake D. McAuliffe, Katrina M. Miranda, Sharon A. Glynn
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
nitric oxide
nitric oxide synthase
tumourigenesis
DNA damage repair
angiogenesis
epithelial to mesenchymal transition
Online Access:https://www.mdpi.com/1422-0067/21/24/9393

Internet

https://www.mdpi.com/1422-0067/21/24/9393

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