Distinct CED-10/Rac1 domains confer context-specific functions in development.

Rac GTPases act as master switches to coordinate multiple interweaved signaling pathways. A major function for Rac GTPases is to control neurite development by influencing downstream effector molecules and pathways. In Caenorhabditis elegans, the Rac proteins CED-10, RAC-2 and MIG-2 act in parallel...

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Bibliographic Details
Main Authors: Steffen Nørgaard, Shuer Deng, Wei Cao, Roger Pocock
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-09-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC6179291?pdf=render