Endoplasmic reticulum stress in the pathogenesis of alcoholic liver disease

The endoplasmic reticulum (ER) plays a pivotal role in protein synthesis, folding, and modification. Under stress conditions such as oxidative stress and inflammation, the ER can become overwhelmed, leading to an accumulation of misfolded proteins and ensuing ER stress. This triggers the unfolded pr...

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Bibliographic Details
Main Authors: Man Na, Xingbiao Yang, Yongkun Deng, Zhaoheng Yin, Mingwei Li
Format: Article
Language:English
Published: PeerJ Inc. 2023-11-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/16398.pdf