Breaking the Mucin Barrier: A New Affinity Chromatography-Mass Spectrometry Approach to Unveil Potential Cell Markers and Pathways Altered in Pseudomyxoma Peritonei

Breaking the Mucin Barrier: A New Affinity Chromatography-Mass Spectrometry Approach to Unveil Potential Cell Markers and Pathways Altered in Pseudomyxoma Peritonei

Abstract Background Pseudomyxoma peritonei (PMP) is a rare peritoneal mucinous carcinomatosis with largely unknown underlying molecular mechanisms. Cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy is the only therapeutic option; however, despite its use, recurrence with...

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Bibliographic Details
Main Authors: Antonio Romero-Ruiz, Melissa Granados-Rodríguez, Florina I. Bura, Francisca Valenzuela-Molina, Blanca Rufián-Andújar, Ana Martínez-López, Lidia Rodríguez-Ortiz, Rosa Ortega-Salas, María Torres-Martínez, Ana Moreno-Serrano, Justo Castaño, Carmen Michán, José Alhama, Mari C. Vázquez-Borrego, Álvaro Arjona-Sánchez
Format: Article
Language:English
Published: BMC 2024-05-01
Series:Biological Procedures Online
Subjects:
Cancer
Mucin
Protein
Pseudomyxoma peritonei
MUC13
Online Access:https://doi.org/10.1186/s12575-024-00239-0

Internet

https://doi.org/10.1186/s12575-024-00239-0

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