A homolog of FHM2 is involved in modulation of excitatory neurotransmission by serotonin in C. elegans.

The C. elegans eat-6 gene encodes a Na(+), K(+)-ATPase alpha subunit and is a homolog of the familial hemiplegic migraine candidate gene FHM2. Migraine is the most common neurological disorder linked to serotonergic dysfunction. We sought to study the pathophysiological mechanisms of migraine and th...

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Bibliographic Details
Main Authors: Elena G Govorunova, Mustapha Moussaif, Andrey Kullyev, Ken C Q Nguyen, Thomas V McDonald, David H Hall, Ji Y Sze
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2860991?pdf=render