Overcoming Metabolic Constraints in the MEP-Pathway Enrich <i>Salvia sclarea</i> Hairy Roots in Therapeutic Abietane Diterpenes

Overcoming Metabolic Constraints in the MEP-Pathway Enrich <i>Salvia sclarea</i> Hairy Roots in Therapeutic Abietane Diterpenes

Abietane diterpenoids (e.g., carnosic acid, aethiopinone, 1-oxoaethiopinone, salvipisone, and ferruginol) synthesized in the roots of several <i>Salvia</i> species have proved to have promising biological activities, but their use on a large scale is limited by the very low content extra...

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Bibliographic Details
Main Authors: Mariaevelina Alfieri, Alfredo Ambrosone, Mariacarmela Vaccaro, Nunziatina De Tommasi, Antonietta Leone
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Applied Sciences
Subjects:
<i>Salvia sclarea</i>
hairy roots
bioactive diterpenes
elicitation
metabolic engineering
Online Access:https://www.mdpi.com/2076-3417/12/14/7116

Internet

https://www.mdpi.com/2076-3417/12/14/7116

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