Chemogenetic inhibition of NTS astrocytes normalizes cardiac autonomic control and ameliorate hypertension during chronic intermittent hypoxia

Chemogenetic inhibition of NTS astrocytes normalizes cardiac autonomic control and ameliorate hypertension during chronic intermittent hypoxia

Abstract Background Obstructive sleep apnea (OSA) is characterized by recurrent episodes of chronic intermittent hypoxia (CIH), which has been linked to the development of sympathoexcitation and hypertension. Furthermore, it has been shown that CIH induced inflammation and neuronal hyperactivation i...

Full description

Bibliographic Details
Main Authors: Katherin Pereyra, Alexandra Las Heras, Camilo Toledo, Esteban Díaz-Jara, Rodrigo Iturriaga, Rodrigo Del Rio
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Biological Research
Subjects:
Obstructive sleep apnea
Intermittent hypoxia
Astrocytes
Nucleus of the solitary tract
Reactive astrocytes
Neuroinflammation
Online Access:https://doi.org/10.1186/s40659-023-00463-0

Internet

https://doi.org/10.1186/s40659-023-00463-0

Similar Items