Divergent immune landscapes of primary and syngeneic Kras-driven mouse tumor models

Abstract Immune cells play critical functions in cancer, and mice with intact immune systems are vital to understanding tumor immunology. Both genetically engineered mouse models (GEMMs) and syngeneic cell transplant approaches use immunocompetent mice to define immune-dependent events in tumor deve...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Wade R. Gutierrez, Amanda Scherer, Gavin R. McGivney, Qierra R. Brockman, Vickie Knepper-Adrian, Emily A. Laverty, Grace A. Roughton, Rebecca D. Dodd
Format: Artykuł
Język:English
Wydane: Nature Portfolio 2021-01-01
Seria:Scientific Reports
Dostęp online:https://doi.org/10.1038/s41598-020-80216-1