Costunolide and Parthenolide Ameliorate MPP+ Induced Apoptosis in the Cellular Parkinson’s Disease Model

Costunolide and Parthenolide Ameliorate MPP+ Induced Apoptosis in the Cellular Parkinson’s Disease Model

Monoamine oxidase B (MAO-B) is an enzyme that metabolizes several chemicals, including dopamine. MAO-B inhibitors are used in the treatment of Parkinson’s Disease (PD), and the inhibition of this enzyme reduces dopamine turnover and oxidative stress. The absence of dopamine results in PD pathogenesi...

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Bibliographic Details
Main Authors: Mehmet Enes Arslan, Hasan Türkez, Yasemin Sevim, Harun Selvitopi, Abdurrahim Kadi, Sena Öner, Adil Mardinoğlu
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Cells
Subjects:
Parkinson’s disease
terpenoids
antioxidants
acetylcholinesterase
apoptosis
Online Access:https://www.mdpi.com/2073-4409/12/7/992

Internet

https://www.mdpi.com/2073-4409/12/7/992

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