Multidrug-resistant tuberculosis control in Rwanda overcomes a successful clone that causes most disease over a quarter century

Multidrug-resistant tuberculosis control in Rwanda overcomes a successful clone that causes most disease over a quarter century

Summary background: Multidrug-resistant (MDR) tuberculosis (TB) poses an important challenge in TB management and control. Rifampicin resistance (RR) is a solid surrogate marker of MDR-TB. We investigated the RR-TB clustering rates, bacterial population dynamics to infer transmission dynamics, and t...

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Bibliographic Details
Main Authors: Jean Claude S. Ngabonziza, Leen Rigouts, Gabriela Torrea, Tom Decroo, Eliane Kamanzi, Pauline Lempens, Aniceth Rucogoza, Yves M. Habimana, Lies Laenen, Belamo E. Niyigena, Cécile Uwizeye, Bertin Ushizimpumu, Wim Mulders, Emil Ivan, Oren Tzfadia, Claude Mambo Muvunyi, Patrick Migambi, Emmanuel Andre, Jean Baptiste Mazarati, Dissou Affolabi, Alaine N. Umubyeyi, Sabin Nsanzimana, Françoise Portaels, Michel Gasana, Bouke C. de Jong, Conor J. Meehan
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
Subjects:
Tuberculosis in Rwanda
Rifampicin-resistant tuberculosis control
Universal drug-susceptibility testing
Mycobacterium tubercuslosis transmission
Online Access:http://www.sciencedirect.com/science/article/pii/S2405579422000043

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http://www.sciencedirect.com/science/article/pii/S2405579422000043

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