Association of CSF GAP-43 and <i>APOE</i> ε4 with Cognition in Mild Cognitive Impairment and Alzheimer’s Disease

Association of CSF GAP-43 and <i>APOE</i> ε4 with Cognition in Mild Cognitive Impairment and Alzheimer’s Disease

The growth-associated protein 43 (GAP-43) is a presynaptic phosphoprotein in cerebrospinal fluid (CSF). The ε4 allele of apolipoprotein E (<i>APOE</i>) is an important genetic risk factor for Alzheimer’s disease (AD). We aimed to evaluate the association of CSF GAP-43 with cognition and...

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Bibliographic Details
Main Authors: Yueli Zhu, Xiaoming Guo, Feng Zhu, Qin Zhang, Yunmei Yang, for the Alzheimer’s Disease Neuroimaging Initiative
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cells
Subjects:
Alzheimer’s disease
growth-associated protein 43
Apolipoprotein E ε4
synaptic loss
biomarker
Online Access:https://www.mdpi.com/2073-4409/12/1/13

Internet

https://www.mdpi.com/2073-4409/12/1/13

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