Inhibition of lysosomal Ca2+ signalling disrupts dendritic spine structure and impairs wound healing in neurons
A growing body of evidence suggests that lysosomes, which have traditionally been regarded as degradative organelles, can function as Ca2+ stores, regulated by the second messenger nicotinic acid adenine dinucleotide phosphate (NAADP). We previously demonstrated that in hippocampal pyramidal neurons...
Main Authors: | , , |
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Formato: | Artigo |
Idioma: | English |
Publicado em: |
Taylor & Francis Group
2017-11-01
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Colecção: | Communicative & Integrative Biology |
Assuntos: | |
Acesso em linha: | http://dx.doi.org/10.1080/19420889.2017.1344802 |