Intestinal Epithelial AMPK Deficiency Causes Delayed Colonic Epithelial Repair in DSS-Induced Colitis

Intestinal Epithelial AMPK Deficiency Causes Delayed Colonic Epithelial Repair in DSS-Induced Colitis

Dysfunctions in the intestinal barrier, associated with an altered paracellular pathway, are commonly observed in inflammatory bowel disease (IBD). The AMP-activated protein kinase (AMPK), principally known as a cellular energy sensor, has also been shown to play a key role in the stabilization and...

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Bibliographic Details
Main Authors: Séverine Olivier, Hanna Diounou, Camille Pochard, Lisa Frechin, Emilie Durieu, Marc Foretz, Michel Neunlist, Malvyne Rolli-Derkinderen, Benoit Viollet
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cells
Subjects:
AMPK
metformin
inflammatory bowel disease
intestinal barrier integrity
epithelium repair
goblet cells
Online Access:https://www.mdpi.com/2073-4409/11/4/590

Internet

https://www.mdpi.com/2073-4409/11/4/590

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