Phosphoproteomic analysis of dengue virus infected U937 cells and identification of pyruvate kinase M2 as a differentially phosphorylated phosphoprotein

Abstract Dengue virus (DENV) is an arthropod-borne Flavivirus that can cause a range of symptomatic disease in humans. There are four dengue viruses (DENV 1 to 4) and infection with one DENV only provides transient protection against a heterotypic virus. Second infections are often more severe as th...

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Bibliographic Details
Main Authors: Jeerang Wongtrakul, Thananya Thongtan, Supitcha Pannengpetch, Nitwara Wikan, Doungnapa Kantamala, Benjawan Kumrapich, Warissara Suwan, Duncan R. Smith
Format: Article
Language:English
Published: Nature Portfolio 2020-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-71407-x