HArmonized single-cell RNA-seq Cell type Assisted Deconvolution (HASCAD)

Abstract Background Cell composition deconvolution (CCD) is a type of bioinformatic task to estimate the cell fractions from bulk gene expression profiles, such as RNA-seq. Many CCD models were developed to perform linear regression analysis using reference gene expression signatures of distinct cel...

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Bibliographic Details
Main Authors: Yen-Jung Chiu, Chung-En Ni, Yen-Hua Huang
Format: Article
Language:English
Published: BMC 2023-10-01
Series:BMC Medical Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12920-023-01674-w