Annual stability of the plasma Aß40/42 ratio and associated factors
Abstract Objective The plasma Aß40/42 ratio is a biomarker of brain amyloidosis. However, the threshold difference between amyloid positivity and negativity is only 10–20% and fluctuates with circadian rhythms, aging, and APOE‐ε4 during the decades of evolution of Alzheimer's disease. Methods P...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2023-06-01
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Series: | Annals of Clinical and Translational Neurology |
Online Access: | https://doi.org/10.1002/acn3.51770 |