A macrophage-cell model of HIV latency reveals the unusual importance of the bromodomain axis

Abstract Background Although macrophages are now recognized as an essential part of the HIV latent reservoir, whether and how viral latency is established and reactivated in these cell types is poorly understood. To understand the fundamental mechanisms of viral latency in macrophages, there is an u...

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Bibliographic Details
Main Authors: Javan K. Kisaka, Daniel Rauch, Malachi Griffith, George B. Kyei
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Virology Journal
Subjects:
Online Access:https://doi.org/10.1186/s12985-024-02343-9