Extracellular Vesicle Biomarkers Reveal Inhibition of Neuroinflammation by Infliximab in Association with Antidepressant Response in Adults with Bipolar Depression

Extracellular Vesicle Biomarkers Reveal Inhibition of Neuroinflammation by Infliximab in Association with Antidepressant Response in Adults with Bipolar Depression

Accumulating evidence suggests that neuroinflammation is involved in bipolar disorder (BD) pathogenesis. The tumor necrosis factor-alpha (TNF-α) antagonist infliximab was recently reported to improve depressive symptoms in a subpopulation of individuals with BD and history of childhood maltreatment....

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Bibliografiska uppgifter
Huvudupphovsmän: Rodrigo B. Mansur, Francheska Delgado-Peraza, Mehala Subramaniapillai, Yena Lee, Michelle Iacobucci, Nelson Rodrigues, Joshua D. Rosenblat, Elisa Brietzke, Victoria E. Cosgrove, Nicole E. Kramer, Trisha Suppes, Charles L. Raison, Sahil Chawla, Carlos Nogueras-Ortiz, Roger S. McIntyre, Dimitrios Kapogiannis
Materialtyp: Artikel
Språk:English
Publicerad: MDPI AG 2020-04-01
Serie:Cells
Ämnen:
bipolar disorder
inflammation
cytokines
childhood trauma
depression
Länkar:https://www.mdpi.com/2073-4409/9/4/895

Internet

https://www.mdpi.com/2073-4409/9/4/895

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