Modification of Homologous Recombination Deficiency Score Threshold and Association with Long-Term Survival in Epithelial Ovarian Cancer

Modification of Homologous Recombination Deficiency Score Threshold and Association with Long-Term Survival in Epithelial Ovarian Cancer

New therapies, such as poly-ADP ribose polymerase inhibitors (PARPi), and immunotherapy treatments have generated great interest in enhancing individualized molecular profiling of epithelial ovarian cancer (EOC) to improve management of the disease. In EOC patients, putative biomarkers for homologou...

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Bibliographic Details
Main Authors: Jeffrey A. How, Amir A. Jazaeri, Bryan Fellman, Molly S. Daniels, Suzanna Penn, Cara Solimeno, Ying Yuan, Kathleen Schmeler, Jerry S. Lanchbury, Kirsten Timms, Karen H. Lu, Melinda S. Yates
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
epithelial ovarian cancer
homologous recombination deficiency
homologous recombination deficiency score
microsatellite instability
tumor mutational burden
survival
Online Access:https://www.mdpi.com/2072-6694/13/5/946

Internet

https://www.mdpi.com/2072-6694/13/5/946

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