Regulatory T cells do not suppress rather activate human basophils by IL-3 and STAT5-dependent mechanisms

Basophils play an important role in orienting Th2 immune response, and in the pathogenesis of allergic and inflammatory disorders. However, the mechanism by which basophils are kept in check remains unclear and hence we explored the role of regulatory T cells (Treg cells) in this process. We demonst...

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Bibliographic Details
Main Authors: Mrinmoy Das, Emmanuel Stephen-Victor, Jagadeesh Bayry
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:OncoImmunology
Subjects:
Online Access:http://dx.doi.org/10.1080/2162402X.2020.1773193