An <named-content content-type="genus-species">Escherichia coli</named-content> Effector Protein Promotes Host Mutation via Depletion of DNA Mismatch Repair Proteins

ABSTRACT Enteropathogenic Escherichia coli (EPEC) is an attaching and effacing (A/E) human pathogen that causes diarrhea during acute infection, and it can also sustain asymptomatic colonization. A/E E. coli depletes host cell DNA mismatch repair (MMR) proteins in colonic cell lines and has been det...

Full description

Bibliographic Details
Main Authors: Oliver David Kenneth Maddocks, Karen Mary Scanlon, Michael S. Donnenberg
Format: Article
Language:English
Published: American Society for Microbiology 2013-07-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00152-13