Recent Advances in Doxorubicin Formulation to Enhance Pharmacokinetics and Tumor Targeting
Doxorubicin (DOX), a widely used drug in cancer chemotherapy, induces cell death via multiple intracellular interactions, generating reactive oxygen species and DNA-adducted configurations that induce apoptosis, topoisomerase II inhibition, and histone eviction. Despite its wide therapeutic efficacy...
Main Authors: | Jihoon Lee, Min-Koo Choi, Im-Sook Song |
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格式: | 文件 |
语言: | English |
出版: |
MDPI AG
2023-05-01
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丛编: | Pharmaceuticals |
主题: | |
在线阅读: | https://www.mdpi.com/1424-8247/16/6/802 |
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