Integration of the beta-catenin-dependent Wnt pathway with integrin signaling through the adaptor molecule Grb2.

THE COMPLEXITY OF WNT SIGNALING LIKELY STEMS FROM TWO SOURCES: multiple pathways emanating from frizzled receptors in response to wnt binding, and modulation of those pathways and target gene responsiveness by context-dependent signals downstream of growth factor and matrix receptors. Both rac1 and...

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Bibliographic Details
Main Authors: Steve P Crampton, Beibei Wu, Edward J Park, Jai-Hyun Kim, Candice Solomon, Marian L Waterman, Christopher C W Hughes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2773007?pdf=render