PCH-2 collaborates with CMT-1 to proofread meiotic homolog interactions.

The conserved ATPase, PCH-2/TRIP13, is required during both the spindle checkpoint and meiotic prophase. However, its specific role in regulating meiotic homolog pairing, synapsis and recombination has been enigmatic. Here, we report that this enzyme is required to proofread meiotic homolog interact...

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Bibliographic Details
Main Authors: Stefani Giacopazzi, Daniel Vong, Alice Devigne, Needhi Bhalla
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-07-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008904