Non-canonical helical transitions and conformational switching are associated with characteristic flexibility and disorder indices in TRP and Kv channels

ABSTRACTStructural evidence and much experimental data have demonstrated the presence of non-canonical helical substructures (π and 310) in regions of great functional relevance both in TRP as in Kv channels. Through an exhaustive compositional analysis of the sequences underlying these substructure...

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Bibliographic Details
Main Authors: Abigail García-Morales, Daniel Balleza
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Channels
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/19336950.2023.2212349