Hypoxic pre-conditioning increases the infiltration of endothelial cells into scaffolds for dermal regeneration pre-seeded with mesenchymal stem cells

Hypoxic pre-conditioning increases the infiltration of endothelial cells into scaffolds for dermal regeneration pre-seeded with mesenchymal stem cells

Many therapies using mesenchymal stem cells (MSC) rely on their ability to produce and release paracrine signals with chemotactic and pro-angiogenic activity. These characteristics, however, are mostly studied under standard in vitro culture conditions. In contrast, various novel cell-based therapie...

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Bibliographic Details
Main Authors: Fernando Antonio Fierro, Adam James O'Neal, Julie Rose Beegle, Myra N Chávez, Thomas Robert Peavy, Roslyn Rivkah Isseroff, Tomás eEgana
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Mesenchymal Stem Cells
Wound Healing
hypoxia
Angiogenesis
scaffolds
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcell.2015.00068/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcell.2015.00068/full

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