Transcriptional regulation of multi-drug tolerance and antibiotic-induced responses by the histone-like protein Lsr2 in M. tuberculosis.

Transcriptional regulation of multi-drug tolerance and antibiotic-induced responses by the histone-like protein Lsr2 in M. tuberculosis.

Multi-drug tolerance is a key phenotypic property that complicates the sterilization of mammals infected with Mycobacterium tuberculosis. Previous studies have established that iniBAC, an operon that confers multi-drug tolerance to M. bovis BCG through an associated pump-like activity, is induced by...

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Bibliographic Details
Main Authors: Roberto Colangeli, Danica Helb, Catherine Vilchèze, Manzour Hernando Hazbón, Chee-Gun Lee, Hassan Safi, Brendan Sayers, Irene Sardone, Marcus B Jones, Robert D Fleischmann, Scott N Peterson, William R Jacobs, David Alland
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-06-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC1894825?pdf=render

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http://europepmc.org/articles/PMC1894825?pdf=render

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