Terahertz and Raman Spectroscopic Investigation of Monohydrate Cocrystal of Antitubercular Isoniazid with Protocatechuic Acid

Terahertz and Raman Spectroscopic Investigation of Monohydrate Cocrystal of Antitubercular Isoniazid with Protocatechuic Acid

Pharmaceutical cocrystal provides an alternative modification strategy for the formulation development of drugs owning to their potential ability to improve the physicochemical properties of active pharmaceutical ingredients (APIs) efficiently by changing inter-molecular interactions between raw mat...

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Bibliographic Details
Main Authors: Yanhua Bo, Jiyuan Fang, Ziming Zhang, Jiadan Xue, Jianjun Liu, Zhi Hong, Yong Du
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Pharmaceutics
Subjects:
isoniazid (INH)
protocatechuic acid (PA)
monohydrate cocrystal
THz time-domain spectroscopy (THz-TDS)
Raman spectroscopy
density functional theory (DFT)
Online Access:https://www.mdpi.com/1999-4923/13/8/1303

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https://www.mdpi.com/1999-4923/13/8/1303

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