Probing the subcutaneous absorption of a PEGylated FUD peptide nanomedicine via in vivo fluorescence imaging

Probing the subcutaneous absorption of a PEGylated FUD peptide nanomedicine via in vivo fluorescence imaging

Abstract The Functional Upstream Domain (FUD) peptide is a potent inhibitor of fibronectin assembly and a therapeutic candidate for disorders linked with hyperdeposition of fibronectin-modulated ECM proteins. Most recently, experiments involving subcutaneous (s.c.) administration of a PEGylated FUD...

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Bibliographic Details
Main Authors: Pawel Zbyszynski, Inger Toraason, Lauren Repp, Glen S. Kwon
Format: Article
Language:English
Published: SpringerOpen 2019-07-01
Series:Nano Convergence
Subjects:
Renal fibrosis
Fibronectin
FUD/pUR4
Subcutaneous drug absorption
Online Access:http://link.springer.com/article/10.1186/s40580-019-0192-3

Internet

http://link.springer.com/article/10.1186/s40580-019-0192-3

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