Eculizumab before and after allogeneic hematopoietic stem cell transplantation in a patient with paroxysmal nocturnal hemoglobinuria

Eculizumab before and after allogeneic hematopoietic stem cell transplantation in a patient with paroxysmal nocturnal hemoglobinuria

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Paroxysmal nocturnal hemoglobinuria (PNH) is characterized by the triad of intravascular hemolysis, venous thrombosis, and cytopenia. Treatment of PNH is generally supportive. Bone marrow transplantation is the only curative therapy for PNH, but is associated with significant morbidity and mortality...

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Bibliographic Details
Main Authors: Hakan Göker, Burak Uz, Yahya Büyükaşık, Salih Aksu, İbrahim Haznedaroğlu, Nilgün Sayınalp, Yasemin Karacan, Fatma Tekin, Osman İlhami Özcebe
Format: Article
Language:English
Published: Galenos Publishing House 2011-08-01
Series:Turkish Journal of Hematology
Subjects:
paroxysmal nocturnal hemoglobinuria
eculizumab
complement
hemolytic episode
Online Access:https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tjh&un=TJH-45403

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https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tjh&un=TJH-45403

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