In silico design and synthesis of targeted rutin derivatives as xanthine oxidase inhibitors

In silico design and synthesis of targeted rutin derivatives as xanthine oxidase inhibitors

Abstract Background Xanthine oxidase is an important enzyme of purine catabolism pathway and has been associated directly in pathogenesis of gout and indirectly in many pathological conditions like cancer, diabetes and metabolic syndrome. In this research rutin, a bioactive flavonoid was explored to...

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Bibliographic Details
Main Authors: Neelam Malik, Priyanka Dhiman, Anurag Khatkar
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Chemistry
Subjects:
Rutin
Xanthine oxidase
Molecular docking
Antioxidant
Online Access:http://link.springer.com/article/10.1186/s13065-019-0585-8

Internet

http://link.springer.com/article/10.1186/s13065-019-0585-8

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