Development and characterization of an enterovirus 71 (EV71) virus-like particles (VLPs) vaccine produced in Pichia pastoris

Development and characterization of an enterovirus 71 (EV71) virus-like particles (VLPs) vaccine produced in Pichia pastoris

Enterovirus 71 (EV71) is one of the major causative agents for hand, foot and mouth disease (HFMD) in children. Although there are three inactivated virus-based HFMD vaccines licensed in China, alternative approaches have been taken to produce an effective and safer vaccine that is easier to manufac...

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Bibliographic Details
Main Authors: Zhijian Yang, Fan Gao, Xiaoliang Wang, Likang Shi, Zheng Zhou, Yuanxiang Jiang, Xinxing Ma, Chao Zhang, Chenliang Zhou, Xianfang Zeng, Ge Liu, Jiang Fan, Qunying Mao, Li Shi
Format: Article
Language:English
Published: Taylor & Francis Group 2020-07-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
enterovirus 71
hand foot and mouth disease
vaccine
immunogenicity
pichia pastoris
virus-like particles
Online Access:http://dx.doi.org/10.1080/21645515.2019.1649554

Internet

http://dx.doi.org/10.1080/21645515.2019.1649554

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