Amidine- and Amidoxime-Substituted Heterocycles: Synthesis, Antiproliferative Evaluations and DNA Binding

Amidine- and Amidoxime-Substituted Heterocycles: Synthesis, Antiproliferative Evaluations and DNA Binding

The novel 1,2,3-triazolyl-appended <i>N</i>- and <i>O</i>-heterocycles containing amidine <b>4</b>–<b>11</b> and amidoxime <b>12</b>–<b>22</b> moiety were prepared and evaluated for their antiproliferative activities in vitro. A...

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Bibliographic Details
Main Authors: Silvija Maračić, Petra Grbčić, Suresh Shammugam, Marijana Radić Stojković, Krešimir Pavelić, Mirela Sedić, Sandra Kraljević Pavelić, Silvana Raić-Malić
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Molecules
Subjects:
amidine
amidoxime
antiproliferative activity
DNA binding
fluorescence
CD spectroscopy
Online Access:https://www.mdpi.com/1420-3049/26/22/7060

Internet

https://www.mdpi.com/1420-3049/26/22/7060

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