Defective microglial development in the hippocampus of Cx3cr1 deficient mice

Defective microglial development in the hippocampus of Cx3cr1 deficient mice

Microglial cells participate in brain development and influence neuronal loss and synaptic maturation. Fractalkine is an important neuronal chemokine whose expression increases during development and that can influence microglia function via the fractalkine receptor, CX3CR1. Mice lacking Cx3cr1 show...

Full description

Bibliographic Details
Main Authors: Francesca ePagani, Rosa ePaolicelli, Emanuele eMurana, Barbara eCortese, Silvia eDi Angelantonio, Emanuele eZurolo, Eva eGuiducci, Tiago A. eFerreira, Stefano eGarofalo, Myriam eCatalano, Giuseppina eD'Alessandro, Alessandra ePorzia, Giovanna ePeruzzi, Fabrizio eMainiero, Cristina eLimatola, Cornelius eGross, Davide eRagozzino
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Microglia
development
rearrangement
Fractalkine
CX3CR1
potassium currents
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00111/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00111/full

Similar Items