Synthesis and in-silico studies of 4-(5-(2-(4-(5-aryl-1,2,4-thiadiazol-3-yl)phenyl)-1H-imidazol-4-yl)-1,3,4-thiadiazol-2-yl)pyridines

Synthesis and in-silico studies of 4-(5-(2-(4-(5-aryl-1,2,4-thiadiazol-3-yl)phenyl)-1H-imidazol-4-yl)-1,3,4-thiadiazol-2-yl)pyridines

4-(5-(2-(4-(5-aryl-1,2,4-thiadiazol-3-yl)phenyl)-1H-imidazol-4-yl)-1,3,4-thiadiazol-2-yl) pyridines were synthesized from benzothioic O-acid and (E)-N'-hydroxy-4-(4-(5-(pyridin-4-yl)-1,3,4-thiadiazol-2-yl)-1H-imidazol-2-yl) benzamidine. New compounds synthesized were characterized by IR, 1H NMR...

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Bibliographic Details
Main Authors: Shashikala Kethireddy, Laxminarayana Eppakayala, Asra Banu Syeda
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Results in Chemistry
Subjects:
Thiadiazole
Imidazole
EGFR inhibitors
Molecular docking
Anticancer agents
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715623005428

Internet

http://www.sciencedirect.com/science/article/pii/S2211715623005428

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