Epigenetic influences on aging: a longitudinal genome-wide methylation study in old Swedish twins

Epigenetic influences on aging: a longitudinal genome-wide methylation study in old Swedish twins

Age-related changes in DNA methylation were observed in cross-sectional studies, but longitudinal evidence is still limited. Here, we aimed to characterize longitudinal age-related methylation patterns using 1011 blood samples collected from 385 Swedish twins (age at entry: mean 69 and standard devi...

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Bibliographic Details
Main Authors: Yunzhang Wang, Robert Karlsson, Erik Lampa, Qian Zhang, Åsa K. Hedman, Malin Almgren, Catarina Almqvist, Allan F. McRae, Riccardo E. Marioni, Erik Ingelsson, Peter M. Visscher, Ian J. Deary, Lars Lind, Tiffany Morris, Stephan Beck, Nancy L. Pedersen, Sara Hägg
Format: Article
Language:English
Published: Taylor & Francis Group 2018-09-01
Series:Epigenetics
Subjects:
dna methylation
aging
longitudinal study
meqtl
twin-pair analysis
Online Access:http://dx.doi.org/10.1080/15592294.2018.1526028

Internet

http://dx.doi.org/10.1080/15592294.2018.1526028

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