Expression estimation and eQTL mapping for HLA genes with a personalized pipeline.
The HLA (Human Leukocyte Antigens) genes are well-documented targets of balancing selection, and variation at these loci is associated with many disease phenotypes. Variation in expression levels also influences disease susceptibility and resistance, but little information exists about the regulatio...
| Hauptverfasser: | , , , , |
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| Format: | Artikel |
| Sprache: | English |
| Veröffentlicht: |
Public Library of Science (PLoS)
2019-04-01
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| Schriftenreihe: | PLoS Genetics |
| Online Zugang: | https://doi.org/10.1371/journal.pgen.1008091 |