Fission yeast Tel1(ATM) and Rad3(ATR) promote telomere protection and telomerase recruitment.
The checkpoint kinases ATM and ATR are redundantly required for maintenance of stable telomeres in diverse organisms, including budding and fission yeasts, Arabidopsis, Drosophila, and mammals. However, the molecular basis for telomere instability in cells lacking ATM and ATR has not yet been elucid...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2009-08-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC2726628?pdf=render |