Protein Deimination Signatures in Plasma and Plasma-EVs and Protein Deimination in the Brain Vasculature in a Rat Model of Pre-Motor Parkinson’s Disease

Protein Deimination Signatures in Plasma and Plasma-EVs and Protein Deimination in the Brain Vasculature in a Rat Model of Pre-Motor Parkinson’s Disease

The identification of biomarkers for early diagnosis of Parkinson’s disease (PD) is of pivotal importance for improving approaches for clinical intervention. The use of translatable animal models of pre-motor PD therefore offers optimal opportunities for novel biomarker discovery in vivo. Peptidylar...

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Bibliographic Details
Main Authors: Marco Sancandi, Pinar Uysal-Onganer, Igor Kraev, Audrey Mercer, Sigrun Lange
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
Peptidylarginine deiminases (PADs)
protein deimination
extracellular vesicles (EVs)
pre-motor Parkinson’s disease
microRNA (miR21, miR155, miR210)
Online Access:https://www.mdpi.com/1422-0067/21/8/2743

Internet

https://www.mdpi.com/1422-0067/21/8/2743

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