TRAF6 promotes chemoresistance to paclitaxel of triple negative breast cancer via regulating PKM2‐mediated glycolysis

Abstract Ample evidence reveals that glycolysis is crucial to tumor progression; however, the underlying mechanism of its drug resistance is still worth being further explored. TRAF6, an E3 ubiquitin ligase, is well recognized to overexpress in various types of cancer, which predicts a poor prognosi...

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Bibliographic Details
Main Authors: Han Xu, Longzhi Li, Bing Dong, Ji Lu, Kun Zhou, Xiaoxing Yin, Huizhen Sun
Format: Article
Language:English
Published: Wiley 2023-10-01
Series:Cancer Medicine
Subjects:
Online Access:https://doi.org/10.1002/cam4.6552