Enhancement of neurogenesis and cognition through intranasal co-delivery of galanin receptor 2 (GALR2) and neuropeptide Y receptor 1 (NPY1R) agonists: a potential pharmacological strategy for cognitive dysfunctions

Enhancement of neurogenesis and cognition through intranasal co-delivery of galanin receptor 2 (GALR2) and neuropeptide Y receptor 1 (NPY1R) agonists: a potential pharmacological strategy for cognitive dysfunctions

Abstract Background Spatial memory deficits and reduced neuronal survival contribute to cognitive decline seen in the aging process. Current treatments are limited, emphasizing the need for innovative therapeutic strategies. This research explored the combined effects of intranasally co-administered...

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Bibliographic Details
Main Authors: Raquel Sánchez-Varo, Alexander López-Salas, Rasiel Beltran-Casanueva, Estela Díaz-Sánchez, Jose Erik Alvarez-Contino, Miguel Angel Barbancho-Fernández, Pedro Serrano-Castro, Kjell Fuxe, Dasiel O. Borroto-Escuela, Natalia García-Casares, Manuel Narváez
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Behavioral and Brain Functions
Subjects:
Neurogenic enhancement
Cognitive enhancement
Intranasal administration
GALR2 agonists
NPY1R agonists
M1145
Online Access:https://doi.org/10.1186/s12993-024-00230-5

Internet

https://doi.org/10.1186/s12993-024-00230-5

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