Temporal and spatial heterogeneity of HER2 status in metastatic colorectal cancer

Temporal and spatial heterogeneity of HER2 status in metastatic colorectal cancer

Abstract Background HER2-targeted therapies have recently emerged as an option in the management of metastatic colorectal cancer (mCRC) overexpressing HER2. However, data regarding HER2 status in primary CRC and its corresponding liver metastases are limited, potentially influencing clinical decisio...

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Bibliographic Details
Main Authors: Flavia D’Angelo, Franck Monnien, Alexis Overs, Irvin Pem, Fanny Dor, Marine Abad, Sophie Felix, Zohair Selmani, Zaher Lakkis, Christophe Borg, Alexandre Doussot, Fréderic Bibeau, Chloé Molimard
Format: Article
Language:English
Published: BMC 2024-06-01
Series:Diagnostic Pathology
Subjects:
Colorectal cancer
HER2
Liver metastasis
Tumor heterogeneity
Online Access:https://doi.org/10.1186/s13000-024-01508-y

Internet

https://doi.org/10.1186/s13000-024-01508-y

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