Exploring Excitotoxicity and Regulation of a Constitutively Active TRP Ca2+ Channel in Drosophila
Unregulated Ca2+ influx affects intracellular Ca2+ homoeostasis, which may lead to neuronal death. In Drosophila, following the activation of rhodopsin the TRP Ca2+ channel is open to mediate the light-dependent depolarization. A constitutively active TRP channel triggers the degeneration of TrpP365...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2021-01-01
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Series: | Fly |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/19336934.2020.1851586 |