The structural impact of cancer-associated missense mutations in oncogenes and tumor suppressors

<p>Abstract</p> <p>Background</p> <p>Current large-scale cancer sequencing projects have identified large numbers of somatic mutations covering an increasing number of different cancer tissues and patients. However, the characterization of these mutations at the structu...

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Bibliographic Details
Main Authors: Lehrach Hans, Wierling Christoph, Duarte José M, Jang Seon-Hi J, Stehr Henning, Lappe Michael, Lange Bodo MH
Format: Article
Language:English
Published: BMC 2011-05-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/10/1/54