Aberrant epigenetic regulators control expansion of human CD34+ hematopoietic stem/progenitor cells

Aberrant epigenetic regulators control expansion of human CD34+ hematopoietic stem/progenitor cells

Transcription is a tightly regulated process ensuring the proper expression of numerous genes regulating all aspects of cellular behavior. Transcription factors regulate multiple genes including other transcription factors that together control a highly complex gene network. The transcriptional mach...

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Bibliographic Details
Main Authors: Farnaz eFaridi, Kanagaraju ePonnusamy, Isabell eQuagliano-Lo Coco, Linping eChen-Wichmann, Manuel eGrez, Reinhard eHenschler, Christian eWichmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-11-01
Series:Frontiers in Genetics
Subjects:
Leukemia
epigenetics
HSPC
stem/progenitor cell expansion
RUNX1/ETO
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00254/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00254/full

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