Novel ACE2 protein interactions relevant to COVID-19 predicted by evolutionary rate correlations

Angiotensin-converting enzyme 2 (ACE2) is the cell receptor that the coronavirus SARS-CoV-2 binds to and uses to enter and infect human cells. COVID-19, the pandemic disease caused by the coronavirus, involves diverse pathologies beyond those of a respiratory disease, including micro-thrombosis (mic...

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Bibliographic Details
Main Authors: Austin A. Varela, Sammy Cheng, John H. Werren
Format: Article
Language:English
Published: PeerJ Inc. 2021-09-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/12159.pdf